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The Discovery of α-Adrenoceptor Antagonists as a Potential New Treatment Option for Uveal Melanoma

Uveal melanoma (UM) is the most common primary intraocular tumor in adults. Because of its high potential for spreading and its limited response to treatment, UM remains a clinical challenge. Previous studies suggest that clinical adrenergic receptor (AR) antagonists might be effective in the treatm...

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Principais autores: Yilan He, Hongtao Liu, Ulrike Hendgen-Cotta, Tienush Rassaf, Nikolaos E. Bechrakis, Utta Berchner-Pfannschmidt
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-10-01
Serier:Biomolecules
Fag:
uveal melanoma
metastasis
adrenergic receptor
α-blockers
prazosin
doxazosin
Online adgang:https://www.mdpi.com/2218-273X/15/10/1436
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