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DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex

BackgroundCocaine use disorder (CUD) is characterized by a loss of control over cocaine intake and is associated with structural, functional, and molecular alterations in the human brain. At the molecular level, epigenetic alterations are hypothesized to contribute to the higher-level functional and...

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Principais autores: Eric Poisel, Lea Zillich, Fabian Streit, Josef Frank, Marion M. Friske, Jerome C. Foo, Naguib Mechawar, Gustavo Turecki, Anita C. Hansson, Markus M. Nöthen, Marcella Rietschel, Rainer Spanagel, Stephanie H. Witt
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-02-01
coleção:Frontiers in Psychiatry
Assuntos:
cocaine
DNA methylation
addiction
epigenetics
EWAS
prefrontal cortex
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1075250/full
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