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Integration of transcriptomics and metabolomics reveals the responses of the maternal circulation and maternal-fetal interface to LPS-induced preterm birth in mice

BackgroundTerm birth (TB) and preterm birth (PTB) are characterized by uterine contractions, rupture of the chorioamniotic membrane, decidual activation, and other physiological and pathological changes. In this study, we hypothesize that inflammation can cause changes in mRNA expression and metabol...

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Principais autores: Xianling Cao, Xuanyou Zhou, Songchang Chen, Chenming Xu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-08-01
Serier:Frontiers in Immunology
Fag:
maternal-fetal interface
transcriptomics
metabolomics
preterm birth
mice
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1213902/full
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