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Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect.

We investigated a polyethylene glycol non-precipitable low-density lipoprotein (LDL) subfraction targeted by IgG and the influence of statin therapy on plasma levels of these small LDL-IgG-immune complexes (LDL-IgG-IC). LDL-subfractions were isolated from 6 atherosclerotic subjects and 3 healthy ind...

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Principais autores: Gerd Hörl, Harald Froehlich, Ulrika Ferstl, Gerhard Ledinski, Josepha Binder, Gerhard Cvirn, Tatjana Stojakovic, Michael Trauner, Christoph Koidl, Erwin Tafeit, Karin Amrein, Hubert Scharnagl, Günther Jürgens, Seth Hallström
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4739583?pdf=render
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