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Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer

Abstract Taxane is a family of front-line chemotherapeutic agents against ovarian cancer (OC). The therapeutic efficacy is frequently counteracted by the development of chemoresistance, leading to high rates of relapse in OC patients. The role(s) of microRNAs (miRNAs) in cancer chemoresistance had b...

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Principais autores: Mohamed K. Hassan, Amr A. Waly, Waheba Elsayed, Sarah Keshk, Walaa Ramadan Allam, Sherif F. El-khamisy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2021-01-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-020-78596-5
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