Structural basis of double-stranded RNA recognition by the J2 monoclonal antibody

Abstract Double-stranded (ds) RNAs are major structural components of the transcriptome, hallmarks of viral infection, and primary triggers of innate immune responses. The J2 monoclonal antibody is the gold-standard method to discover and map endogenous dsRNAs across subcellular locations and cell s...

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Autors principals:	Charles Bou-Nader, Kevin M. Juma, Ankur Bothra, Andrew J. Brasington, Rodolfo Ghirlando, Motoshi Suzuki, David N. Garboczi, Stephen H. Leppla, Jinwei Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-67414-z
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