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Comparative analysis of genetic variants in pleural fluids and solid tissue biopsies of pleural mesothelioma patients: Implications for molecular heterogeneity assessment

Objectives: This study aims to determine whether the sequencing of DNA extracted from pleural fluids (PFs) of Pleural Mesothelioma (PM) patients accurately represents the genetic information obtained from the solid tissue counterpart biopsies with particular attention to the identification of single...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Roberto Silvestri, Filomena Rea, Marianna Vitiello, Gabriele Moretti, Vittorio Aprile, Marco Lucchi, Paolo Aretini, Chiara Maria Mazzanti, Stefano Landi, Federica Gemignani
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-06-01
Schriftenreihe:Heliyon
Schlagworte:
Liquid biopsies
Pleural mesothelioma
Cancer-specific mutations
Whole-exome sequencing
Tumour heterogeneity
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2405844024081830
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