Malic enzymes in cancer: Regulatory mechanisms, functions, and therapeutic implications

Malic enzymes (MEs) are metabolic enzymes that catalyze the oxidation of malate to pyruvate and NAD(P)H. While researchers have well established the physiological metabolic roles of MEs in organisms, recent research has revealed a link between MEs and carcinogenesis. This review collates evidence of...

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Detalhes bibliográficos

Principais autores:	Huan Wang, Wanlin Cui, Song Yue, Xianglong Zhu, Xiaoyan Li, Lian He, Mingrong Zhang, Yan Yang, Minjie Wei, Huizhe Wu, Shuo Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-09-01
coleção:	Redox Biology
Assuntos:	Malic enzymes Cancer Drug resistance Cancer therapy Malic enzyme inhibitors
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231724002519
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