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Integrating Hi-C links with assembly graphs for chromosome-scale assembly.

Long-read sequencing and novel long-range assays have revolutionized de novo genome assembly by automating the reconstruction of reference-quality genomes. In particular, Hi-C sequencing is becoming an economical method for generating chromosome-scale scaffolds. Despite its increasing popularity, th...

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Bibliografiske detaljer
Principais autores: Jay Ghurye, Arang Rhie, Brian P Walenz, Anthony Schmitt, Siddarth Selvaraj, Mihai Pop, Adam M Phillippy, Sergey Koren
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2019-08-01
Serier:PLoS Computational Biology
Online adgang:https://doi.org/10.1371/journal.pcbi.1007273
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