Marine Compounds Selectively Induce Apoptosis in Female Reproductive Cancer Cells but Not in Primary-Derived Human Reproductive Granulosa Cells

Anticancer properties of tyrindoleninone and 6-bromoisatin from Dicathais orbita were tested against physiologically normal primary human granulosa cells (HGC) and reproductive cancer cell lines. Tyrindoleninone reduced cancer cell viability with IC50 values of 39 µM (KGN; a tumour-derived granulosa...

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Autores principales:	Fiona Young, Kirsten Benkendorff, Vicki Edwards
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2012-01-01
Colección:	Marine Drugs
Materias:	gynaecological cancers brominated indoles marine mollusc apoptosis
Acceso en línea:	http://www.mdpi.com/1660-3397/10/1/64/
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