MECOM promotes supporting cell proliferation and differentiation in cochlea

Permanent damage to hair cells (HCs) is the leading cause of sensory deafness. Supporting cells (SCs) are essential in the restoration of hearing in mammals because they can proliferate and differentiate to HCs. MDS1 and EVI1 complex locus (MECOM) is vital in early development and cell differentiati...

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Библиографические подробности
Главные авторы: Peipei Chen, Na Zuo, Cheng Wu, Jun Ma, Yao Li, Junfei Gu, Wen Li, Shaofeng Liu
Формат: Artigo
Язык:Inglês
Опубликовано: Tsinghua University Press 2022-04-01
Серии:Journal of Otology
Предметы:
MECOM
Supporting cells
Regeneration
Proliferation
Hair cells
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1672293021000611
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