Validation of a methylation-based, tissue-free MRD assay in colorectal cancer patients from the GALAXY study

Abstract This study validates a methylation-based, tissue-free assay (LatitudeTM assay) for detecting molecular residual disease (MRD) in colorectal cancer (CRC), analyzing data from 195 patients (1230 timepoints) from the observational GALAXY study. The assay demonstrated that ctDNA-positivity corr...

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Egile Nagusiak:	Yoshiaki Nakamura, Johannes G. Reiter, Prashanthi Natarajan, Joshua Babiarz, Preethi Srinivasan, Jayashree Joshi, Yu Lin, Tzu-Chun Chen, Nathan Liang, Su Maw, Ehsan Haghshenas, Garima Kushwaha, Boris Gutman, Ilker Tunc, Wen-Ching Chan, Antony Tin, Yuefan Huang, Sara L. Bristow, Meenakshi Malhotra, Shruti Sharma, Stephanie A. Sanchez, Adham Jurdi, Minetta C. Liu, Trupti Kawli, Matthew Rabinowitz, Alexey Aleshin, Daisuke Kotani, Oki Eiji, Takayuki Yoshino
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2026-01-01
Saila:	npj Precision Oncology
Sarrera elektronikoa:	https://doi.org/10.1038/s41698-026-01277-5
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