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Beyond the Lesion: Back to High Fidelity DNA Synthesis

High fidelity (HiFi) DNA polymerases (Pols) perform the bulk of DNA synthesis required to duplicate genomes in all forms of life. Their structural features, enzymatic mechanisms, and inherent properties are well-described over several decades of research. HiFi Pols are so accurate that they become s...

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Bibliografiske detaljer
Principais autores: Joseph D. Kaszubowski, Michael A. Trakselis
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-01-01
Serier:Frontiers in Molecular Biosciences
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2021.811540/full
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