Global huntingtin knockout in adult mice leads to fatal neurodegeneration that spares the pancreas
Recent reports on the consequences of global HTT knock-out have discrepant findings. We confirm here that early loss of HTT leads to subcortical calcification, which is preceded by induction of circulating neurofilament light chain levels, but find no pancreatitis. Huntington’s disease (HD) is a fat...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Life Science Alliance LLC
2024-09-01
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| Serier: | Life Science Alliance |
| Online adgang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202402571 |
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