CD169+ lymph node macrophages have protective functions in mouse breast cancer metastasis

Summary: Although the contribution of macrophages to metastasis is widely studied in primary tumors, the involvement of macrophages in tumor-draining lymph nodes (LNs) in this process is less clear. We find CD169+ macrophages as the predominant macrophage subtype in naive LNs, which undergo prolifer...

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Detalhes bibliográficos

Principais autores:	Carlotta Tacconi, Catharina D. Commerford, Lothar C. Dieterich, Simon Schwager, Yuliang He, Kristian Ikenberg, Ekaterina Friebel, Burkhard Becher, Sònia Tugues, Michael Detmar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-04-01
coleção:	Cell Reports
Assuntos:	lymph node macrophages tumor-associated macrophages distant organ metastasis tumor-draining lymph node breast cancer metastasis CD169+ macrophages
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124721003077
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