Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

Abstract Gastric cancer (GC) is the third leading cause of cancer‐related deaths worldwide. Helicobacter pylori (H. pylori) infection is a crucial initiative factor for the Correa cascade occurrence of GC. However, the immunological mechanisms of H. pylori‐induced GC remain incompletely understood,...

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Hauptverfasser:	Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-02-01
Schriftenreihe:	View
Schlagworte:	FYB1 gastric carcinogenesis Helicobacter pylori immune microenvironment scRNA‐seq
Online-Zugang:	https://doi.org/10.1002/VIW.20250101
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