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Context-specific eQTLs provide deeper insight into causal genes underlying shared genetic architecture of COVID-19 and idiopathic pulmonary fibrosis

Summary: Most genetic variants identified through genome-wide association studies (GWASs) are suspected to be regulatory in nature, but only a small fraction colocalize with expression quantitative trait loci (eQTLs, variants associated with expression of a gene). Therefore, it is hypothesized but l...

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Hlavní autoři: Trisha Dalapati, Liuyang Wang, Angela G. Jones, Jonathan Cardwell, Iain R. Konigsberg, Yohan Bossé, Don D. Sin, Wim Timens, Ke Hao, Ivana Yang, Dennis C. Ko
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2025-04-01
Edice:HGG Advances
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2666247725000132
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