Dysregulated tRNA-derived fragments impair fatty acid metabolism in intrahepatic cholestasis of pregnancy

ObjectiveIntrahepatic cholestasis of pregnancy (ICP) is a common obstetric complication that occurs predominantly in the mid-to-late gestational period, but its exact etiology remains unclear. Recent studies have revealed that transfer RNA-derived fragments (tRFs) are closely associated with various...

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Váldodahkkit:	Lian Yang, Xia Yu, Shimao Zhang, Jinzhu Fu, Mengjun Luo, Wei Shen, Cheng Huang, Xiao Yang
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2025-07-01
Ráidu:	Frontiers in Medicine
Fáttát:	intrahepatic cholestasis of pregnancy (ICP) tRNA-derived small RNAs (tsRNAs) tRNA-derived fragments (tRFs) fatty acid total bile acid (TBA)
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1630677/full
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