HDAC6 Deacetylates Ku70 and Regulates Ku70-Bax Binding in Neuroblastoma
Ku70 was first characterized as a nuclear factor that binds DNA double-strand breaks in nonhomolog end-joining DNA repair. However, recent studies have shown that Ku70 is also found in the cytoplasm and binds Bax, preventing Bax-induced cell death. We have shown that, in neuroblastoma cells, the bin...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2011-08-01
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| Edice: | Neoplasia: An International Journal for Oncology Research |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S1476558611800072 |
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