Increased Cerebrospinal Fluid Lactate Levels in Schizophrenia and Major Depressive Disorder: NCNP Biobank Study in Japan

ABSTRACT Aim Altered brain energy metabolism related to neural hyperexcitation, which leads to increased lactate levels in the brain and cerebrospinal fluid (CSF), has been implicated in several neuropsychiatric disorders. This study aimed to investigate CSF levels of lactate and related metabolites...

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Autori principali:	Hideo Hagihara, Kotaro Hattori, Hiroshi Kunugi, Tsuyoshi Miyakawa
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-03-01
Serie:	Neuropsychopharmacology Reports
Soggetti:	cerebrospinal fluid major depressive disorder metabolism neural hyperexcitation schizophrenia
Accesso online:	https://doi.org/10.1002/npr2.70096
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