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Ad-VT causes ovarian cancer A2780 cell death via mitochondrial apoptosis and autophagy pathways

Objective: The recombinant adenovirus Ad-apoptin-hTERTp-E1a (Ad-VT) to have a bi-specific oncolytic character in many tumor cells, but its action pathway in killing tumor cells has not been accurately elucidated. Here, we studied the mechanism of apoptosis and autophagy induced by Ad-VT and the inte...

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Autori principali: Yingli Cui, Xin Chen, Wenjie Li, Shanzhi Li, Ningyi Jin, Xiao Li, Yiquan Li, Ying Yue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-10-01
Serie:Translational Oncology
Soggetti:
Recombinant adenovirus
Apoptin
Ovarian cancer
Apoptosis
Autophagy
Accesso online:http://www.sciencedirect.com/science/article/pii/S1936523324001943
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