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Low-Dose Total Body Irradiation Can Enhance Systemic Immune Related Response Induced by Hypo-Fractionated Radiation

A systemic immune related response (SIME) of radiotherapy has been occasionally observed on metastatic tumors, but the clinical outcomes remain poor. Novel treatment approaches are therefore needed to improve SIME ratio. We used a combination of hypo-fractionated radiation therapy (H-RT) with low-do...

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Principais autores: Jing Liu, Jie Zhou, Min Wu, ChuanFei Hu, Juan Yang, Dong Li, Peng Wu, Yue Chen, Ping Chen, Sheng Lin, YongXia Cui, ShaoZhi Fu, JingBo Wu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-02-01
coleção:Frontiers in Immunology
Assuntos:
systemic immune related response
hypo-fractionated radiation therapy
low-dose total body irradiation
immune enhancement
immunosuppressive microenvironment
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.00317/full
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