4579 Distinct clinical and immunological responses to αPD-1, kαPD-L1 and αPD-L2 immunotherapy in B16 melanoma in aged versus young hosts includes T-cell stem cell effects and PD-L2 expression differences
OBJECTIVES/GOALS: Aging is the biggest risk factor for cancer, yet little is known about cancer immunotherapy effects. Here we investigate melanoma response to αPD-1, αPD-L1 and αPD-L2 in young vs. aged hosts. We look at different immune outcomes as possible mechanism. METHODS/STUDY POPULATION: We t...
Guardado en:
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cambridge University Press
2020-06-01
|
| Colección: | Journal of Clinical and Translational Science |
| Acceso en línea: | https://www.cambridge.org/core/product/identifier/S2059866120000631/type/journal_article |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|