G12/13-mediated signaling stimulates hepatic glucose production and has a major impact on whole body glucose homeostasis

Abstract Altered hepatic glucose fluxes are critical during the pathogenesis of type 2 diabetes. G protein-coupled receptors represent important regulators of hepatic glucose production. Recent studies have shown that hepatocytes express GPCRs that can couple to G12/13, a subfamily of heterotrimeric...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Srinivas Pittala, Dhanush Haspula, Yinghong Cui, Won-Mo Yang, Young-Bum Kim, Roger J. Davis, Allison Wing, Yaron Rotman, Owen P. McGuinness, Asuka Inoue, Jürgen Wess
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2024-11-01
Sarja:	Nature Communications
Linkit:	https://doi.org/10.1038/s41467-024-54299-7
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!