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Saffron as a natural modulator of reverse cholesterol transport genes in atherosclerotic rabbits, with molecular docking insights

Abstract Atherosclerosis is a major contributor to cardiovascular disease, and one of the mechanisms that contributes to atherosclerosis is the reverse cholesterol transport (RCT) pathway, which includes SR-BI, ABCA1, and PPARγ genes. Natural compounds that modulate RCT-related genes may present pro...

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Hoofdauteurs: Yasmin Mohd Zainal Abidin Shukri, Iman Nabilah Abd Rahim, Suhaila Abd Muid, Siti Azma Jusoh, Nurul Alimah Abdul Nasir, Che Puteh Osman, Monaliza Mat Tahir, Noorul Izzati Hanafi, Noor Alicezah Mohd Kasim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2025-12-01
Reeks:Scientific Reports
Onderwerpen:
Saffron
Atherosclerosis
Reverse cholesterol transport
Gene expression
Molecular docking
Cholesterol metabolism
Online toegang:https://doi.org/10.1038/s41598-025-32622-6
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