An examination of the relationship between hotspots and recombination associated with chromosome 21 nondisjunction.

Trisomy 21, resulting in Down Syndrome (DS), is the most common autosomal trisomy among live-born infants and is caused mainly by nondisjunction of chromosome 21 within oocytes. Risk factors for nondisjunction depend on the parental origin and type of meiotic error. For errors in the oocyte, increas...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Tiffany Renee Oliver, Candace D Middlebrooks, Stuart W Tinker, Emily Graves Allen, Lora J H Bean, Ferdouse Begum, Eleanor Feingold, Reshmi Chowdhury, Vivian Cheung, Stephanie L Sherman
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Public Library of Science (PLoS) 2014-01-01
Reeks:	PLoS ONE
Online toegang:	http://europepmc.org/articles/PMC4057233?pdf=render
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!