TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice.

Helminths are highly prevalent metazoan parasites that infect over a billion of the world's population. Hosts have evolved numerous mechanisms to drive the expulsion of these parasites via Th2-driven immunity, but these responses must be tightly controlled to prevent equally devastating immunopathol...

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Principais autores:	Nicola Steel, Aduragbemi A Faniyi, Sayema Rahman, Stefanie Swietlik, Beata I Czajkowska, Bethany T Chan, Alexander Hardgrave, Anthony Steel, Tim D Sparwasser, Mushref B Assas, Richard K Grencis, Mark A Travis, John J Worthington
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2019-04-01
Serija:	PLoS Pathogens
Online dostop:	https://doi.org/10.1371/journal.ppat.1007657
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