Epithelial hypusination regulates Helicobacter pylori-induced gastric inflammation

Abstract Hypusine is a unique amino acid synthesized on the eukaryotic initiation factor 5 A (EIF5A) from the polyamine spermidine by deoxyhypusine synthase (DHPS). Hypusination of EIF5A plays a key role in translation. Here, we examined the contribution of the epithelial hypusination pathway to gas...

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Principais autores:	Alain P. Gobert, Kara M. McNamara, Caroline V. Hawkins, Mohammad Asim, Daniel P. Barry, Alberto G. Delgado, Kristie L. Rose, Purvi Patel, Regina N. Tyree, Kate S. Carson, Lori A. Coburn, M. Blanca Piazuelo, Keith T. Wilson
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer 2026-02-01
Series:	Amino Acids
Assuntos:	Infection Gastritis Polyamines Hypusine Proteome
Acceso en liña:	https://doi.org/10.1007/s00726-026-03496-3
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