Association of obesity risk SNPs in <it>PCSK1 </it>with insulin sensitivity and proinsulin conversion
<p>Abstract</p> <p>Background</p> <p>Prohormone convertase 1 is involved in maturation of peptides. Rare mutations in gene <it>PCSK1</it>, encoding this enzyme, cause childhood obesity and abnormal glucose homeostasis with elevated proinsulin concentrations. Common single nucleotide polymorphisms (S...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2010-06-01
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| Col·lecció: | BMC Medical Genetics |
| Accés en línia: | http://www.biomedcentral.com/1471-2350/11/86 |
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