Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells

The endocannabinoid system (ECS) exerts immunosuppressive effects, which are mostly mediated by cannabinoid receptor 2 (CBR2), whose expression on leukocytes is higher than CBR1, mainly localized in the brain. Targeted CBR2 activation could limit inflammation, avoiding CBR1-related psychoactive effe...

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Bibliografski detalji

Glavni autori:	Antonella Capozzi, Daniela Caissutti, Vincenzo Mattei, Francesca Gado, Stefano Martellucci, Agostina Longo, Serena Recalchi, Valeria Manganelli, Gloria Riitano, Tina Garofalo, Maurizio Sorice, Clementina Manera, Roberta Misasi
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-12-01
Serija:	Molecules
Teme:	CB2R agonist CB2R immunomodulation anti-inflammatory activity
Online pristup:	https://www.mdpi.com/1420-3049/27/1/64
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