A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device

Three-dimensional (3D) models with cells arranged in clusters or spheroids have emerged as valuable tools to improve physiological relevance in drug screening. One of the challenges with cells cultured in 3D, especially for high-throughput applications, is to quickly and non-invasively assess the ce...

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Bibliographic Details

Main Authors:	Jonas Christoffersson, Florian Meier, Henning Kempf, Kristin Schwanke, Michelle Coffee, Mario Beilmann, Robert Zweigerdt, Carl-Fredrik Mandenius
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2018-05-01
Series:	Bioengineering
Subjects:	3D cell culture microfluidics organ-on-a-chip cardiac spheroids cardiomyocytes induced pluripotent stem cells (iPSCs) drug screening
Online Access:	http://www.mdpi.com/2306-5354/5/2/36
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