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The ParaHox gene Cdx4 induces acute erythroid leukemia in mice

Abstract: Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the ParaHox gene CDX4 is expressed in patients with acute erythroid leukemia, and that aberrant expression of Cdx4 induced homogenously a...

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Autors principals: Silvia Thoene, Tamoghna Mandal, Naidu M. Vegi, Leticia Quintanilla-Martinez, Reinhild Rösler, Sebastian Wiese, Klaus H. Metzeler, Tobias Herold, Torsten Haferlach, Konstanze Döhner, Hartmut Döhner, Luisa Schwarzmüller, Ursula Klingmüller, Christian Buske, Vijay P.S. Rawat, Michaela Feuring-Buske
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019-11-01
Col·lecció:Blood Advances
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2473952920317717
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