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Combination of Tramadol with Minocycline Exerted Synergistic Effects on a Rat Model of Nerve Injury-Induced Neuropathic Pain

Neuropathic pain is a refractory clinical problem. Certain drugs, such as tramadol, proved useful for the treatment of neuropathic pain by inhibiting the activity of nociceptive neurons. Moreover, studies indicated that suppression or modulation of glial activation could prevent or reverse neuropath...

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Autors principals: Xiao-Peng Mei, Lei Chen, Wei Wang, Dan Wu, Li-Ying Wang, Ting Zhang, Hui Zhang, Li-Xian Xu, Yun-Qing Li
Format: Artigo
Idioma:Inglês
Publicat: Cell Physiol Biochem Press GmbH & Co KG 2012-09-01
Col·lecció:Neurosignals
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Accés en línia:http://www.karger.com/Article/FullText/338049
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