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The GPR68-NINJ1 axis: an emerging mechano-chemical checkpoint in blood–brain barrier disruption—a hypothetical framework and therapeutic promise

The blood–brain barrier (BBB) is a critical interface whose failure is a convergent pathological feature of traumatic, ischemic, and neurodegenerative neurological diseases. Current paradigms often overlook the synergistic interplay between mechanical forces and biochemical cues, such as acidosis, t...

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Bibliografiske detaljer
Principais autores: Boren Bai, Haixiao Feng, Huimin Yang, Maokui Huang, Yuechun Wang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-03-01
Serier:Frontiers in Cellular Neuroscience
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fncel.2026.1757822/full
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