SRPK Inhibitors Reduce the Phosphorylation and Translocation of SR Protein Splicing Factors, thereby Correcting BIN1, MCL-1 and BCL2 Splicing Errors and Enabling Apoptosis of Cholangiocarcinoma Cells

Background: Cholangiocarcinoma (CCA) is a malignancy of the bile duct epithelium that is commonly found in the Thai population. CCA has poor prognosis and a low survival rate due to the lack of early diagnosis methods and the limited effectiveness of current treatments. A number o...

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Autores principales:	Preenapan Changphasuk, Chaturong Inpad, Sukanya Horpaopan, Sasiprapa Khunchai, Suchada Phimsen, Damratsamon Surangkul, Tavan Janvilisri, Atit Silsirivanit, Worasak Kaewkong
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	IMR Press 2024-09-01
Colección:	Frontiers in Bioscience-Scholar
Materias:	alternative splicing apoptosis cholangiocarcinoma srpk srsf
Acceso en línea:	https://www.imrpress.com/journal/FBS/16/3/10.31083/j.fbs1603017
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