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CT-based radiomic nomogram for preoperative prediction of DNA mismatch repair deficiency in gastric cancer

BackgroundDNA mismatch repair (MMR) deficiency has attracted considerable attention as a predictor of the immunotherapy efficacy of solid tumors, including gastric cancer. We aimed to develop and validate a computed tomography (CT)-based radiomic nomogram for the preoperative prediction of MMR defic...

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Principais autores: Qingwen Zeng, Yanyan Zhu, Leyan Li, Zongfeng Feng, Xufeng Shu, Ahao Wu, Lianghua Luo, Yi Cao, Yi Tu, Jianbo Xiong, Fuqing Zhou, Zhengrong Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-09-01
coleção:Frontiers in Oncology
Assuntos:
gastric cancer (GC)
radiomics
microsatellite instability
nomogram
LASSO
DNA mismatch repair deficiency
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.883109/full
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