Placental cytochrome P450 methylomes in infants exposed to prenatal opioids: exploring the effects of neonatal opioid withdrawal syndrome on health horizons

Background: Neonatal opioid withdrawal syndrome (NOWS), arises due to increased opioid use during pregnancy. Cytochrome P450 (CYP) enzymes play a pivotal role in metabolizing a wide range of substances in the human body, including opioids, other drugs, toxins, and endogenous compounds. The associati...

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Principais autores:	Uppala Radhakrishna, Senthilkumar Sadhasivam, Rupa Radhakrishnan, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Saumya Patel, Rakesh M. Rawal, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh, Swapan K. Nath
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2024-01-01
Series:	Frontiers in Genetics
Assuntos:	cytochromes biomarker opioid use neonatal opioid withdrawal syndrome CYP19A1 CYP1A2 CYP4V2
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1292148/full
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