Chemotherapy receipt in affected BRCA1/2 and PALB2 carriers with operable breast cancer: the impact of early detection and pre-diagnostic awareness on clinical outcomes and treatment

Abstract Purpose While enhanced breast screening of germline pathogenic variant (GPV) carriers results in earlier stage at diagnosis, the impact of tumour biology and GPV on chemotherapy receipt in early-stage disease remains understudied. Methods We retrospectively reviewed treatment administered f...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Stephanie M. Wong, Carla Apostolova, Amina Ferroum, Basmah Alhassan, Ipshita Prakash, Mark Basik, Karyne Martel, Sarkis Meterissian, David Fleiszer, Nora Wong, Michaela Bercovitch Sadinsky, Talia Malagon, Jean Francois Boileau, William D. Foulkes
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2025-04-01
سلاسل:	Hereditary Cancer in Clinical Practice
الموضوعات:	Breast neoplasms BRCA1/2 Hereditary breast cancer Chemotherapy
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13053-025-00314-x
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!