Trajectories of physical function prior to death and brain neuropathology in a community-based cohort: the act study

Abstract Background Mechanisms linking cognitive and physical functioning in older adults are unclear. We sought to determine whether brain pathological changes relate to the level or rate of physical performance decline. Methods This study analyzed data from 305 participants in the autopsy subcohor...

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Autori principali:	Andrea Z. LaCroix, Rebecca A. Hubbard, Shelly L. Gray, Melissa L. Anderson, Paul K. Crane, Joshua A. Sonnen, Oleg Zaslavsky, Eric B. Larson
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-11-01
Serie:	BMC Geriatrics
Soggetti:	Physical function Functional decline Brain neuropathology Alzheimer’s disease Vascular dementia
Accesso online:	http://link.springer.com/article/10.1186/s12877-017-0637-7
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