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The Anti-proliferative and Pro-apoptotic Effects of Iranian Viper Venom (Vipera raddei kurdistanica) on Human Gastric Cancer Cells (C615) are Mediated by PI3K/AKT/mTOR Signalling Pathway Inhibition

Objective: Gastric cancer (GC) is one of the most common malignancies worldwide. Since the PI3K/AKT/mTORsignalling pathway plays a crucial role in tumour growth and survival, this study aims to evaluate the anti-proliferativeand pro-apoptotic effects of Vipera raddei kurdistanica venom on human GC c...

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Principais autores: Cyrus Jalili, Mona Pazhouhi, Mohammadreza Gholami, Fuzieh Khani-Hemmatabadi, Keyvan Maleki
Format: Artigo
Sprog:Inglês
Udgivet: Royan Institute (ACECR), Tehran 2025-12-01
Serier:Cell Journal
Fag:
apoptosis
cancer
signalling pathway
viper venom
Online adgang:https://www.celljournal.org/article_733462_692b2f153516ce93e824b7ba789935d9.pdf
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