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Cellular stress modulates severity of the inflammatory response in lungs via cell surface BiP

Inflammation is a central pathogenic feature of the acute respiratory distress syndrome (ARDS) in COVID-19. Previous pathologies such as diabetes, autoimmune or cardiovascular diseases become risk factors for the severe hyperinflammatory syndrome. A common feature among these risk factors is the sub...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Gustavo Rico-Llanos, Óscar Porras-Perales, Sandra Escalante, Daniel B. Vázquez-Calero, Lucía Valiente, María I. Castillo, José Miguel Pérez-Tejeiro, David Baglietto-Vargas, José Becerra, José María Reguera, Ivan Duran, Fabiana Csukasi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2022-11-01
Rangatū:Frontiers in Immunology
Ngā marau:
COVID-19
acute respiratory distress syndrome
binding-immunoglobulinprotein (BiP/GRP78/HSPA5)
cytokine storm
cell surface GRP78 (csGRP78)
cellular stress
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1054962/full
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