The Omega‐6 Lipid pathway shift is associated with neutrophil influx and structural lung damage in early cystic fibrosis lung disease

Abstract Objectives In cystic fibrosis (CF), an imbalanced lipid metabolism is associated with lung inflammation. Little is known about the role that specific lipid mediators (LMs) exert in CF lung inflammation, and whether their levels change during early disease progression. Therefore, we measured...

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Hauptverfasser:	Lisa JM Slimmen, Jelle Y Broos, Badies HAN Manaï, Silvia C Estevão, Martin Giera, Gijs Kooij, Wendy WJ Unger, Hettie M Janssens
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2024-09-01
Schriftenreihe:	Clinical & Translational Immunology
Schlagworte:	alveolar macrophages cystic fibrosis inflammasome lipid mediators neutrophils translational immunology
Online-Zugang:	https://doi.org/10.1002/cti2.70000
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