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Small molecule Photoregulin3 prevents retinal degeneration in the RhoP23H mouse model of retinitis pigmentosa

Regulation of rod gene expression has emerged as a potential therapeutic strategy to treat retinal degenerative diseases like retinitis pigmentosa (RP). We previously reported on a small molecule modulator of the rod transcription factor Nr2e3, Photoregulin1 (PR1), that regulates the expression of p...

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Bibliografische Detailangaben
Hauptverfasser: Paul A Nakamura, Andy A Shimchuk, Shibing Tang, Zhizhi Wang, Kole DeGolier, Sheng Ding, Thomas A Reh
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2017-11-01
Schriftenreihe:eLife
Schlagworte:
Online-Zugang:https://elifesciences.org/articles/30577
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