Computational pathology identifies immune-mediated collagen disruption to predict clinical outcomes in gynecologic malignancies

Abstract Background The role of immune cells in collagen degradation within the tumor microenvironment (TME) is unclear. Immune cells, particularly tumor-infiltrating lymphocytes (TILs), are known to alter the extracellular matrix, affecting cancer progression and patient survival. However, the quan...

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Autors principals:	Arpit Aggarwal, Sirvan Khalighi, Deepak Babu, Haojia Li, Sepideh Azarianpour-Esfahani, Germán Corredor, Pingfu Fu, Mojgan Mokhtari, Tilak Pathak, Elizabeth Thayer, Susan Modesitt, Haider Mahdi, Stefanie Avril, Anant Madabhushi
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-01-01
Col·lecció:	Communications Medicine
Accés en línia:	https://doi.org/10.1038/s43856-023-00428-0
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