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Brain glucose hypometabolism and hippocampal inflammation in Goto-Kakizaki rats

Brain glucose hypometabolism and neuroinflammation are early pathogenic manifestations in neurological disorders. Neuroinflammation may also disrupt leptin signaling, an adipokine that centrally regulates appetite and energy balance by acting on the hypothalamus and exerting neuroprotection in the h...

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Autori principali: J.C.O. Borges, V.A.B. Oliveira, T.D.A. Serdan, F.L.R. Silva, C.S. Santos, J.R.B. Pauferro, A.S.F. Ribas, R. Manoel, A.C.G. Pereira, I.S. Correa, J.N.B. Pereira, R.B. Bazotte, A.C. Levada-Pires, T.C. Pithon-Curi, R. Gorjão, R. Curi, S.M. Hirabara, L.N. Masi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Associação Brasileira de Divulgação Científica 2023-06-01
Serie:Brazilian Journal of Medical and Biological Research
Soggetti:
Insulin resistance
Cognitive disorders
Hyperglycemia
Hippocampus
Leptin
Goto-Kakizaki rats
Accesso online:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100640&tlng=en
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