Camptothecin shows better promise than Curcumin in the inhibition of the Human Telomerase: A computational study

Objectives: The Human Telomerase enzyme has become a drug target in the treatment of cancers and age-related disorders. This study aims to identify potential natural inhibitors of the Human Telomerase from compounds derived from edible African plants. Materials and methods: A library of 1,126 natura...

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Autors principals:	Adekunle Babajide Rowaiye, Yoroshi Joana Teca Mendes, Samson Ayodeji Olofinsae, John Breakthrough Oche, Oluwakemi Hannah Oladipo, Okiemute Ajiroghene Okpalefe, Joyce Oloaigbe Ogidigo
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2021-08-01
Col·lecció:	Heliyon
Matèries:	Telomerase Molecular dynamic simulation Pharmacokinetic Augustamine Camptothecin
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405844021018454
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