The dual effects of iron deficiency on intervertebral disc development and on acute injury-induced disc degeneration

Abstract Clinical studies have reported that anemic patients with lower back pain exhibit significantly more severe lumbar intervertebral disc (IVD) degeneration compared to non-anemic individuals. Given that iron deficiency (ID) is the leading cause of anemia, we hypothesized that ID may disrupt IV...

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Autors principals:	Hengrui Chang, Shaomeng Kang, Chenchen Li, Lihui Wu, Hongran Liu, Di Zhang, Yanzhong Chang
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-06-01
Col·lecció:	Scientific Reports
Matèries:	Iron deficiency Intervertebral disc degeneration Anemia Intervertebral disc development
Accés en línia:	https://doi.org/10.1038/s41598-025-04388-4
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