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MUC1 drives ferroptosis resistance in ICC via Src‐mediated FSP1 deubiquitination and myristoylation

Abstract Background Intrahepatic cholangiocarcinoma (ICC) exhibits poor prognosis and limited therapeutic options. Ferroptosis represents a promising therapeutic strategy, yet resistance mechanisms remain poorly understood. This study investigated the role of mucin 1 (MUC1) in regulating ferroptosis...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Yuqiao Zhao, Shifeng Yang, Lei Huang, Xuyun Liu, Qixiang Han, Qichao Niu, Siyi Li, Chuanlie Zhou, Boshi Sun, Yanmei Yang, Xinyu Zhang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2025-10-01
Seri Bilgileri:Clinical and Translational Medicine
Konular:
ferroptosis
intrahepatic cholangiocarcinoma
MUC1
post‐translational modification
Online Erişim:https://doi.org/10.1002/ctm2.70495
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