Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models

Abstract Background Immunocompetent animal models are required to study tumor-host interactions, immunotherapy, and immunotherapeutic combinations, however the currently available immunocompetent lung cancer models have substantial limitations. While orthotopic models potentially help fill this gap,...

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Autori principali:	Kyle Nolan, Gregory Verzosa, Tim Cleaver, Darinee Tippimanchai, Lisa N. DePledge, Xiao-Jing Wang, Christian Young, Anh Le, Robert Doebele, Howard Li, Stephen P. Malkoski
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-08-01
Serie:	Cancer Cell International
Soggetti:	Lung cancer Mouse models Orthotopic murine lung cancer models
Accesso online:	http://link.springer.com/article/10.1186/s12935-020-01503-5
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