Asymmetric synthesis of stereogenic-at-sulfur compounds via biocatalytic oxidation with Unspecific Peroxygenases

Abstract Stereogenic-at-sulfur compounds are vitally important biologically active small molecules, with many drugs featuring chiral sulfur atoms. Methods for the asymmetric synthesis of sulfoxide centres are well established, but methods that produce enantiomerically enriched sulfoximines and sulfi...

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Hlavní autoři:	Jiacheng Li, Benjamin Melling, Katy A. S. Cornish, Nicholas Mulholland, Jared Cartwright, William P. Unsworth, Gideon Grogan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-12-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-67405-0
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